The X-Men are back. And this time in a time of war! They were born with a unique genetic mutation that allows them to wield supernatural powers. Under the influence of Professor Charlwes Xavier (Patrick Stewart), they serve humanity. They protect the world. But the world distrusts and fears them. After a senseless assassination attempt on the President of the United States, allegedly by an unknown mutant, the public calls for a law to bring the mutants under control The movement is led by army commander and scientist William Stryker (Brian Cox), who is said to have experimented on mutants.
He hates mutants and intends to eliminate them completely. When he discovers that his own son is a mutant, he kills him without mercy. Stryker has also dealt with Wolverine (Hugh Jackman) in the past and knows the secret of his past. As Wolverine searches for his origins, Stryker sets his anti-mutant agenda in motion. However, there are mutants who have taken a stand against human civilization. One of them, Magneto (Ian McKellen), has just escaped from prison. He is an enemy of the X-MEN. With all the mutants having become scum, he proposes an alliance to the X-MEN against their common enemy, Stryker. Together, the X-MEN and their allies embark on the most dangerous mission of their lives...
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